Sublingual Cialis and original Cialis – What’s the difference?

Sublingual Cialis entered the pharmaceutical market in 2003 after getting FDA approval as a medicine recommended for the treatment of erectile dysfunction in men. The drug was developed by American pharmaceutical giant Eli Lilly, the scientists of which had developed a new PDE-5 inhibitor that had got a name Tadalafil.

Tadalafil is a synthesized active substance which action is very similar to that of Sildenafil citrate that is known as a main component of famous Viagra. Both these substances block phosphodiesterase type 5 enzyme, in such a way increasing the level of other enzyme, cyclic guanosine monophosphate. Classical cGMP regulatory role is to stimulate muscle cell relaxation, thus contributing to increased blood flow to tissues. Since PDE-5 is mainly concentrated in the tissues of penis (in cavernous bodies in particular), inhibiting it Tadalafil provides enhancing blood supply to penis and owing to this it hardens and increases in volume.

Though Tadalafil mechanism of action is similar to other PDE-5 inhibitors, its chemical structure differs a little and dew to this fact Cialis have got a unique feature – the longest action period among all existing ED drugs. It lasts for 36 hours against 4-5 hours promised by Viagra. That’s why Cialis got a name of «weekend pills» and gained popularity comparable to famous Viagra.

Sublingual Viagra becomes the next step in the development of the popular ED medicine. The new drug contains the same active substance, Tadalafil, in the sufficient amount to ensure stable and long-lasting erection, but its formula was changed with aim to make its use more comfortable for patients. The matter is that being the ED drug with the longest effect duration original Cialis doesn’t work as fast as its sublingual analogue. The mean maximum concentration of original Cialis makes up 2 hours though the first effect of the drug is usually observed in 15-20 minutes after intake.

Sublingual Viagra is dissolved under the tongue and its active substance starts absorbing almost at once through blood vessels located in the mouth cavity. Thus there is no need to wait when the drug gets into the stomach and then the process of absorption starts. This form of administration allows Sublingual Viagra to act faster than the original drug. Besides, Sublingual Viagra is influenced by fatty food and alcohol consumption to a lesser extent since they don’t interact in the stomach. In addition, a lot of men find it more comfortable to dissolve the drug under the tongue than to swallow it. That’s why they choose Sublingual Viagra as more convenient and fast medicine.

Though Sublingual Viagra is manufactured by another pharmaceutical company its quality meets international standards and this is proved by proper tests which the medicine has to pass before entering the market. So it is the safe and effective ED drug with some improved properties developed to enhance male potency in the most comfortable and the fastest way.

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